Zu "871026-44-7" wurden 2 Artikel gefunden!

Für die Filterung wurden keine Ergebnisse gefunden!
TAK-285
TAK-285

Artikelnummer: SYN-1153-M001

Soluble in DMSO or ethanol. TAK-285 is a novel investigational dual HER2/EGFR inhibitor with IC(50) values of 17 and 23nM, respectively. Target: EGFR - HER2 , Kinase Group: RTK , Substrate: Tyrosine
Schlagworte: TAK285
Anwendung: EGFR / HER2 inhibitor
CAS 871026-44-7
MW: 548 D
ab 218,00 €
Bewerten
TAK-285
TAK-285

Artikelnummer: Cay29157-1

TAK-285 is a dual inhibitor of EGFR and HER2 (IC50s = 23 and 17 nM, respectively). It is selective for EGFR and HER2 over a panel of 36 kinases (IC50s = 250->10,000 nM). TAK-285 inhibits the proliferation of BT474 breast cancer cells (GI50 = 17 nM) as well as induces tumor regression in a 4-1st gastric...
Schlagworte: N-[2-[4-[[3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl]amino]-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-3-hydroxy-3-methyl-b...
Anwendung: EGFR / HER2 dual inhibitor
CAS 871026-44-7
MW: 548 D
ab 39,00 €
Bewerten