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AC-261066
AC-261066

Artikelnummer: Cay43589-10

AC-261066 is a retinoic acid receptor beta2 (RARbeta2) agonist. It selectively induces RARbeta2 activity over RARbeta1 activity in functional assays using mammalian cells (EC50s = 10 and >10,000 nM, respectively). AC-261066 is also selective for RARbeta over RARalpha and RARgamma (EC50s = 12, 70, and 33 nM,...
Schlagworte: 4-[4-(2-butoxyethoxy)-5-methyl-2-thiazolyl]-2-fluoro-benzoic acid
Anwendung: RARbeta2 agonist
CAS 870773-76-5
MW: 353.41 D
ab 103,00 €
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AC-261066
AC-261066

Artikelnummer: TGM-T14089-100mg

Description: AC-261066 is an orally available and isoform-selective agonist of RARbeta2 with a pEC50 of 8.0. Target: Retinoid Receptor. Smiles: CCCCOCCOc1nc(sc1C)-c1ccc(C(O)=O)c(F)c1. References: Lund BW, et al. Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. J...
Schlagworte: AC 261066
CAS 870773-76-5
MW: 353.41 D
ab 30,00 €
Bewerten