Zu "867160-71-2" wurden 3 Artikel gefunden!
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Linsitinib
Artikelnummer: Cay17708-1
The binding of insulin-like growth factor 1 (IGF-1) to the IGF-1 receptor (IGF-1R) promotes cell growth while inhibiting apoptotic pathways. Overexpression of IGF-1R is found in certain solid tumors and hematologic neoplasias. However, insulin receptor (InsR) signaling can compensate for IGF-1R inhibition....
| Schlagworte: | OSI-906, cis-3-[8-amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol |
| Anwendung: | IGF-1R & InsR kinase inhibitor |
| CAS | 867160-71-2 |
| MW: | 421.5 D |
ab 60,00 €
OSI-906
Artikelnummer: LKT-O7333.5
IGF-1R and InsR inhibitor.
| Schlagworte: | OSI906, Linsitinib |
| Anwendung: | Insulin-like growth factor 1 receptor |
| CAS | 867160-71-2 |
| MW: | 421.49 D |
ab 136,00 €
Linsitinib
Artikelnummer: TGM-T6017-100mg
Description: OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of...
| Schlagworte: | OSI-906 |
| Anwendung: | Targets insulin-like growth factor 1 receptor [EC:2.7.10.1] (IGF1R, CD221) |
| CAS | 867160-71-2 |
| MW: | 421.49 D |
ab 32,00 €
