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TC-S 7001
Artikelnummer: Cay19129-1
TC-S 7001 is an inhibitor of Rho-associated kinase (ROCK, IC50s = 0.6 and 1.1 nM, respectively, for human ROCK1 and ROCK2). It is selective for ROCK over myosin light-chain kinase (MLCK) and zipper-interacting protein kinase (ZIP-kinase, IC50s = 7,400 and 4,100 nM, respectively), as well as 110 kinases in a panel at...
| Schlagworte: | Azaindole 1, 6-chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine |
| Anwendung: | ROCK inhibitor |
| CAS | 867017-68-3 |
| MW: | 402.8 D |
ab 180,00 €
ROCK-IN-2
Artikelnummer: TGM-TQ0110-100mg
Description: ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2. Target: ROCK. Smiles: Cc1c[nH]c2nccc(Oc3c(F)cc(Nc4cc(Cl)nc(N)n4)cc3F)c12. References: Kast R, et al. Cardiovascular effects of a novel potent and highly selective...
| Schlagworte: | Azaindole 1, TC-S 7001 |
| Anwendung: | ROCK inhibitor |
| CAS | 867017-68-3 |
| MW: | 402.79 D |
ab 109,00 €
