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Quarfloxin
Quarfloxin

Artikelnummer: Cay36552-1

Quarfloxin is an inhibitor of RNA polymerase I-mediated transcription. It binds to G-quadruplex DNA and inhibits the interaction between ribosomal DNA G-quadruplexes and nucleolin, a nucleolar protein required for RNA polymerase I-mediated transcription. Quarfloxin (10 µM) induces nucleolin mislocalization from the...
Schlagworte: CX-3543, Itarnafloxin, Quarfloxacin,...
Anwendung: RNA polymerase I-mediated transcription inhibitor, antineoplastic, topoisomerase II inhibitor
CAS 865311-47-3
MW: 604.7 D
ab 82,00 €
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