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A-740003
Artikelnummer: TGM-T3690-100mg
Description: A-740003 (A 740003) is an effective and specific P2X7 receptor antagonist (IC50: 18/40 nM, for rat/human). It can reduce nociception in animal models of persistent neuropathic and inflammatory pain, and also reduce neuroblastoma tumor growth in mice. Target: P2X Receptor. Smiles:...
| Schlagworte: | A 740003 |
| Anwendung: | P2RX7 antagonist |
| CAS | 861393-28-4 |
| MW: | 474.55 D |
ab 34,00 €
A-740003
Artikelnummer: Cay21256-10
A-740003 is a competitive antagonist of the ATP-gated ionotropic P2X7 receptor (IC50s = 40 and 18 nM for human and rat receptors, respectively). It shows weak or no activity at other P2 receptors and other receptors and ion channels. A-740003 blocks agonist-induced IL-1beta release and pore formation in...
| Schlagworte: | N-[1-[[(cyanoamino)(5-quinolinylimino)methyl]amino]-2,2-dimethylpropyl]-3,4-dimethoxy-benzeneacetamide |
| Anwendung: | P2RX7 antagonist |
| CAS | 861393-28-4 |
| MW: | 474.6 D |
ab 44,00 €
