Zu "859212-16-1" wurden 3 Artikel gefunden!
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Bafetinib
Artikelnummer: Cay19169-1
Bcr-Abl, a fusion protein with deregulated tyrosine kinase activity, is highly expressed in chronic myelogenous leukemia (CML). Bafetinib is a rationally developed tyrosine kinase inhibitor based on the chemical structure of imatinib (Cay-13139), with modifications added to improve binding and potency against...
| Schlagworte: | INNO-406, NS-187,... |
| Anwendung: | Bcr-Abl tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor |
| CAS | 859212-16-1 |
| MW: | 576.6 D |
ab 67,00 €
Bafetinib
Artikelnummer: SYN-1179-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl, Lyn inhibitor with IC(50) values of 5.8nM and 19nM, respectively.
| Schlagworte: | NS-187, INNO-406 |
| Anwendung: | Bcr-Abl / Lyn inhibitor |
| CAS | 859212-16-1 |
| MW: | 576,6 D |
ab 154,00 €
Bafetinib
Artikelnummer: TGM-T6311-100mg
Description: Bafetinib (INNO-406) (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR. Target: Autophagy, Src, Bcr-Abl. Smiles:...
| Schlagworte: | NS-187, INNO-406 |
| Anwendung: | Targets abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (ABL1) |
| CAS | 859212-16-1 |
| MW: | 576.62 D |
ab 30,00 €
