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AT7867
Artikelnummer: Cay16848-10
AT7867 is a potent and orally bioavailable inhibitor of Akt isoforms Akt1, 2, and 3 (IC50s = 32, 17, and 47 nM, respectively). It also inhibits p70S6 kinase and PKA (IC50s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases. AT7867 inhibits growth and induces apoptosis in a variety...
| Schlagworte: | 4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]-piperidine |
| Anwendung: | Akt Inhibitor |
| CAS | 857531-00-1 |
| MW: | 337.9 D |
ab 142,00 €
