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AT7867
Artikelnummer: Cay16848-10
AT7867 is a potent and orally bioavailable inhibitor of Akt isoforms Akt1, 2, and 3 (IC50s = 32, 17, and 47 nM, respectively). It also inhibits p70S6 kinase and PKA (IC50s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases. AT7867 inhibits growth and induces apoptosis in a variety...
| Schlagworte: | 4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]-piperidine |
| Anwendung: | Akt Inhibitor |
| CAS | 857531-00-1 |
| MW: | 337.9 D |
ab 158,00 €
AT7867
Artikelnummer: TGM-T6304-100mg
Description: AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 values of 32 nM, 17 nM, 47 nM, 85 nM, and 20 nM, respectively, exhibiting little activity outside the AGC kinase family. Target: S6 Kinase, PKA, Akt. Smiles: Clc1ccc(cc1)C1(CCNCC1)c1ccc(cc1)-c1cn[nH]c1. References:...
| Anwendung: | Akt Inhibitor |
| CAS | 857531-00-1 |
| MW: | 337.85 D |
ab 36,00 €
