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K252c
Artikelnummer: Cay13514-10
K252c is a cell-permeable PKC inhibitor (IC50s = 2.45 and 25.7 µM for PKC and PKA, respectively). It induces apoptosis in human chronic myelogenous leukemia cancer cells. In human foreskin fibroblast cells, it reduces focus formation induced by human cytomegalovirus (HCMV) strains sensitive and resistant to...
| Schlagworte: | SD 1825, Staurosporine aglycone, 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one |
| Anwendung: | Protein kinase C inhibitor |
| CAS | 85753-43-1 |
| MW: | 311.3 D |
ab 130,00 €
![K252c (6,7,12,13-Tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one, Staurosporine Aglycone, St](https://www.biomol.com/media/image/72/7b/81/K0000-60-1_200x200.jpg "K252c (6,7,12,13-Tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one, Staurosporine Aglycone, St")
K252c...
Artikelnummer: K0000-60.1
Inhibits PKC with IC50 of 2.5uM and PKA at about 10-fold higher concentrations. Solubility: Soluble DMSO. , Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
| CAS | 85753-43-1 |
| MW: | 311.34 |
208,00 €
K-252c
Artikelnummer: AG-CN2-0097-M001
Off-white to yellow crystalline solid. Soluble in DMSO or methanol. Insoluble in water. Indolocarbazole alkaloid antibiotic., Potent cell permeable reversible and ATP-competitive PKC (protein kinase C) inhibitor with 10-fold selectivity over PKA (protein kinase A), Anticancer compound. Cytotoxic againt various...
| Schlagworte: | Staurosporine aglycone, Staurosporinone, Antibiotic K252c, 6,7,12,13-Tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one |
| Anwendung: | Indolocarbazole alkaloid antibiotic, PKC inhibitor |
| CAS | 85753-43-1 |
| MW: | 311,4 D |
ab 77,00 €
K252C
Artikelnummer: LKT-K0023.1
K252c inhibits protein kinase C.
| Anwendung: | PKC inhibitor |
| CAS | 85753-43-1 |
| MW: | 311,34 D |
ab 329,00 €
K-252c
Artikelnummer: TGM-T15638-10mg
Description: K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 µM). K-252c also inhibits beta-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia cancer cells. Target: PKC. Smiles:...
| Anwendung: | Indolocarbazole alkaloid antibiotic, PKC inhibitor |
| CAS | 85753-43-1 |
| MW: | 311.34 D |
ab 807,00 €
