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(-)-Rolipram
(-)-Rolipram

Artikelnummer: Cay31111-1

(-)-Rolipram is a phosphodiesterase 4 (PDE4) inhibitor (IC50 = 0.22 µM for the guinea pig eosinophil enzyme) and an enantiomer of (±)-rolipram (Cay-10011132). It enhances isoprenaline-induced cAMP accumulation in isolated guinea pig eosinophils (EC50 = 0.19 µM). (-)-Rolipram (1-1,000 µM) inhibits TNF and INF-gamma...
Schlagworte: (R)-(-)-Rolipram, (R)-Rolipram, (4R)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
Anwendung: PDE4 inhibitor
CAS 85416-75-7
MW: 275.3 D
ab 56,00 €
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(R)-(-)-Rolipram
(R)-(-)-Rolipram

Artikelnummer: TGM-T13448-10mg

Description: (R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor. Target: DNA-PK, Others. Smiles: COc1ccc(cc1OC1CCCC1)[C@@H]1CNC(=O)C1. References: Guo C, et al. Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. Immunity. 2016 Oct...
Schlagworte: (R)-Rolipram, (-)-Rolipram
Anwendung: PDE4 inhibitor
CAS 85416-75-7
MW: 275.34 D
ab 38,00 €
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