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BML-284
Artikelnummer: TGM-T3144-5mg
Description: BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator. Target: Wnt/beta-catenin. Smiles: COc1cccc(c1)-c1cc(NCc2ccc3OCOc3c2)nc(N)n1. References: Angew Chem Int Ed Engl. 2005, 44(13), 1987-1990.
| Schlagworte: | Wnt agonist 1 |
| Anwendung: | Cell-permeable Wnt signaling activator |
| CAS | 853220-52-7 |
| MW: | 350.37 D |
ab 55,00 €
Wnt Agonist I
Artikelnummer: Cay19903-10
Wnt Agonist I is a cell-permeable activator of Wnt signaling that does not inhibit GSK3beta (IC50 > 60 µM). It induces nuclear accumulation of beta-catenin, increasing transcriptional activity driven by TCF (EC50 = 700 nM) and altering embryonic development. Wnt Agonist I is effective in vivo, decreasing tissue...
| Schlagworte: | BML-284, N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine |
| Anwendung: | Cell-permeable Wnt signaling activator |
| CAS | 853220-52-7 |
| MW: | 350.4 D |
ab 128,00 €
