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Galeterone
Artikelnummer: Cay17586-5
The cytochrome P450 (CYP) isoform CYP17 is also known as steroid 17alpha-hydroxylase/17,20 lyase because it catalyzes both 17alpha-hydroxylase and 17,20 lyase reactions in the synthesis of steroids, including androgens, estrogens, glucocorticoids, and mineralocorticoids. Galeterone is a CYP17 inhibitor (IC50 = 300...
| Schlagworte: | TOK-001, 17-(1H-benzimidazol-1-yl)-androsta-5,16-dien-3beta-ol |
| Anwendung: | CYP17 inhibitor |
| CAS | 851983-85-2 |
| MW: | 388.6 D |
ab 38,00 €
Galeterone
Artikelnummer: TGM-T6509-100mg
Description: Galeterone (VN 124) is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential antiandrogen activity. Galeterone exhibits three distinct mechanisms of action: 1) as an androgen receptor antagonist, 2) as a CYP17 lyase inhibitor and 3) by decreasing...
| Schlagworte: | VN-124-1, VN/124-1, VN 124, TOK-001 |
| Anwendung: | Targets steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase (CYP17A) |
| CAS | 851983-85-2 |
| MW: | 388.55 D |
ab 49,00 €
