Zu "849217-68-1" wurden 4 Artikel gefunden!
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XL184
Artikelnummer: Cay18464-1
XL184 is an inhibitor of VEGFR2 (IC50 = 0.035 nM). It is selective for VEGFR2 over Ron, EGFR, IGF-1R, and EphA4/B4, but also inhibits c-Met, RET, c-Kit, Axl, FLT3, and Tie2 (IC50s = 1.3, 5.2, 4.6, 7, 11.3, and 14.3 nM, respectively). XL184 (4.6 nM) inhibits VEGF-induced tubule formation in human microvascular...
| Schlagworte: | BMS-907351, Cabozantinib, N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Anwendung: | Pan tyrosine kinase inhibitor |
| CAS | 849217-68-1 |
| MW: | 501.5 D |
ab 60,00 €
Cabozantinib
Artikelnummer: LKT-C0006.10
Cabozantinib or XL-184 is a tyrosine kinase (c-MET, VEGFR2) inhibitor. It has been shown to reduce tumor growth, metastasis, angiogenesis, and induce apoptosis.
| Schlagworte: | XL-184, BMS-907351, N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
| CAS | 849217-68-1 |
| MW: | 501.51 D |
ab 121,00 €
Cabozantinib, Free Base (BMS-907351, Cometriq, XL-184,...
Artikelnummer: LC-C-8901_100mg
Soluble in DMSO
| Schlagworte: | BMS-907351, Cabozantinib, N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Anwendung: | Pan tyrosine kinase inhibitor |
| CAS | 849217-68-1 |
| MW: | 501,51 D |
ab 86,00 €
Cabozantinib
Artikelnummer: CDX-C0755-M010
Cabozantinib is a potent multi-targeted receptor tyrosine kinase (RTK) inhibitor of endothelial growth factor receptor 2 (VEGFR2) (IC50=0.035nM), the hepatocyte growth factor receptor c-Met (IC50=1.3nM), AXL (IC50=7nM), fms like tyrosine kinase 3 (FLT3) (IC50=11.3nM), mast/stem cell growth factor (KIT) (IC50=4.6nM),...
| Schlagworte: | BMS-907351, XL184 |
| Anwendung: | Potent multi-targeted receptor tyrosine kinase (RTK) inhibitor |
| CAS | 849217-68-1 |
| MW: | 501.5 D |
ab 168,00 €
