Zu "849217-68-1" wurden 4 Artikel gefunden!

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XL184
XL184

Artikelnummer: Cay18464-1

XL184 is a pan tyrosine kinase inhibitor that primarily targets VEGFR2 (IC50 = 0.035 nM) and c-Met (IC50 = 1.3 nM) but also inhibits RET, c-Kit, Axl, FLT3, and Tie2 (IC50s = 5.2, 4.6, 7, 11.3, and 14.3 nM, respectively). In in vivo breast, lung, and glioma tumor models that represent dysregulated c-Met and VEGFR...
Schlagworte: BMS-907351, Cabozantinib, N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
Anwendung: Pan tyrosine kinase inhibitor
CAS 849217-68-1
MW: 501.5 D
ab 44,00 €
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Cabozantinib
Cabozantinib

Artikelnummer: LKT-C0006.10

Cabozantinib or XL-184 is a tyrosine kinase (c-MET, VEGFR2) inhibitor. It has been shown to reduce tumor growth, metastasis, angiogenesis, and induce apoptosis.
Schlagworte: XL-184, BMS-907351, N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
CAS 849217-68-1
MW: 501.51 D
ab 92,00 €
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Cabozantinib, Free Base (BMS-907351, Cometriq, XL-184, CAS 849217-68-1), >99%
Cabozantinib, Free Base (BMS-907351, Cometriq, XL-184,...

Artikelnummer: LC-C-8901_100mg

Soluble in DMSO
Schlagworte: BMS-907351, Cabozantinib, N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
Anwendung: Pan tyrosine kinase inhibitor
CAS 849217-68-1
MW: 501,51 D
ab 75,00 €
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Cabozantinib
Cabozantinib

Artikelnummer: SYN-1138-M001

Soluble in DMSO or ethanol. Cabozantinib is very potent inhibitor, with an IC(50) of less than 10nM for VEGFR2, MET, Kit and FLT3-ITD.
Schlagworte: XL184, BMS-907351
Anwendung: VEGFR-2 inhibitor
CAS 849217-68-1
MW: 501,5 D
ab 86,00 €
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