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PTACH
Artikelnummer: TGM-T3199-100mg
Description: PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 µM). Target: HIV Protease, HDAC. Smiles: N(C(CCCCCCSC(C(C)C)=O)=O)C1=NC(=CS1)C2=CC=CC=C2. References: Suzuki T, et al. J Med Chem. 2005 Feb 24,48(4):1019-32.
| Schlagworte: | NCH-51, Cpd 51 |
| Anwendung: | HDAC inhibitor |
| CAS | 848354-66-5 |
| MW: | 390.56 D |
ab 43,00 €
![PTACH [NCH 51]](https://www.biomol.com/media/image/d3/00/64/AG-CR1-3667-M005_200x200.png "PTACH [NCH 51]")
PTACH [NCH 51]
Artikelnummer: AG-CR1-3667-M005
Synthetic. Chemical. CAS: 848354-66-5. Formula: C20H26N2O2S2. MW: 390.56. Synthetic. Potent non-hydroxamate HDAC inhibitor (HDACi) (IC50: 32, 48 and 41nM for HDAC4, HDAC1 and HDAC6, respectively). Cell-permeable prodrug that is intracellularly converted to the potent HDAC inhibitor NCH 31. Predicted to exhibit a...
| Schlagworte: | Cpd 51, S-(7-Oxo-7-((4-phenylthiazol-2-yl)amino)heptyl) 2-methylpropanethioate |
| Anwendung: | HDAC inhibitor |
| CAS | 848354-66-5 |
| MW: | 390,56 D |
ab 88,00 €
PTACH
Artikelnummer: CDX-P0063-M005
White crystals. Soluble in DMSO (25mg/ml). Non-hydroxamate HDAC inhibitor (HDACi) (IC50: 32, 48 and 41nM for HDAC4, HDAC1 and HDAC6, respectively). Cell-permeable prodrug that is intracellularly converted to a potent HDAC inhibitor. Predicted to exhibit a similar HDAC binding mode as that of SAHA, interacting with...
| Schlagworte: | NCH 51, Cpd 51, S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate |
| Anwendung: | HDAC inhibitor |
| CAS | 848354-66-5 |
| MW: | 390,56 D |
ab 145,00 €
NCH-51
Artikelnummer: Cay21234-1
NCH-51 is an inhibitor of histone deacetylases (HDACs) with IC50 values of 48, 32, and 41 nM for HDAC1, 4, and 6, respectively. It increases acetylation of histone H4 and alpha-tubulin in HCT116 cells when used at concentrations ranging from 1 to 25 µM and inhibits the growth of a variety of cancer cell lines (EC50s...
| Schlagworte: | PTACH, S-[7-oxo-7-[(4-phenyl-2-thiazolyl)amino]heptyl] ester, 2-methyl-propanethioic acid |
| Anwendung: | HDAC inhibitor |
| CAS | 848354-66-5 |
| MW: | 390.6 D |
ab 36,00 €
