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CJ-42794
Artikelnummer: TGM-T14975-10mg
Description: CJ-42794 (CJ-042794) is a selective antagonist of the prostaglandin E receptor subtype 4 (EP4), inhibiting [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5. It exhibits a binding affinity that is at least 200-fold more selective for the human EP4 receptor than for other human EP...
| Schlagworte: | CJ-042794 |
| Anwendung: | EP4 receptor agonist |
| CAS | 847728-01-2 |
| MW: | 413.83 D |
ab 33,00 €
CJ-42794
Artikelnummer: Cay10010428-10
Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CJ-42794 is a selective antagonist of EP4 (Ki = 3.16 nM) that less...
| Schlagworte: | RQ-00015986, 4-[(1S)-1-[[5-chloro-2-(4-fluorophenoxy)benzoyl]amino]ethyl]-benzoic acid |
| Anwendung: | EP4 receptor agonist |
| CAS | 847728-01-2 |
| MW: | 413.8 D |
ab 73,00 €
