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ML-385
Artikelnummer: Cay21114-5
ML-385 is an inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2, IC50 = 1.9 µM) that blocks downstream target gene expression. It substantially enhances cytotoxicity in non-small cell lung cancer (NSCLC) cells treated with platinum-based drugs. ML-385 shows specificity and selectivity for NSCLC cells...
| Schlagworte: | N-[4-[2,3-dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide |
| Anwendung: | NRF2 inhibitor |
| CAS | 846557-71-9 |
| MW: | 511.6 D |
ab 139,00 €
ML385
Artikelnummer: TGM-T4360-5mg
Description: ML385 is an NRF2 inhibitor (IC50=1.9 µM) with novelty and specificity. ML385 has anti-inflammatory activity by modulating anti-oxidative stress through the inhibition of NRF2. ML385 also exhibits anti-tumor activity. Target: Others, Ferroptosis, Nrf2. Smiles:...
| Anwendung: | NRF2 inhibitor |
| CAS | 846557-71-9 |
| MW: | 511.59 D |
ab 45,00 €
