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Napabucasin
Artikelnummer: TGM-T3218-100mg
Description: Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor. Target: STAT. Smiles: CC(=O)c1cc2c(o1)C(=O)c1ccccc1C2=O. References: Li Y, et al. Proc Natl Acad Sci U S A. 2015, 112(6), 1839-1844.
| Schlagworte: | BBI608 |
| Anwendung: | Targets signal transducer and activator of transcription 3 (STAT3) |
| CAS | 83280-65-3 |
| MW: | 240.21 D |
ab 60,00 €
Napabucasin
Artikelnummer: Cay22255-5
Napabucasin is an inhibitor of cancer cell stemness. It reduces growth in a panel of cancer cells enriched for high stemness (IC50s = 0.291-1.249 µM) and decreases protein and gene expression of various self-renewal and pro-survival markers including Nanog, Smo, Axl, Atm, and Bmi-1 in a concentration-dependent...
| Schlagworte: | BBI 608, 2-acetyl-naphtho[2,3-b]furan-4,9-dione |
| Anwendung: | Antineoplastic, STAT3 inhibitor |
| CAS | 83280-65-3 |
| MW: | 240.2 D |
ab 94,00 €
