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APD668
Artikelnummer: TGM-T2088-100mg
Description: APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively. Target: GPR, Potassium Channel, P450. Smiles: CC(C)OC(=O)N1CCC(CC1)Oc1ncnc2n(ncc12)-c1ccc(cc1F)S(C)(=O)=O. References: Semple G, et al. Bioorg Med Chem Lett. 2011 May 15,21(10):3134-41.
| Schlagworte: | APD 668 |
| CAS | 832714-46-2 |
| MW: | 477.51 D |
ab 45,00 €
APD668
Artikelnummer: Cay17642-5
GPR119, a glucose-dependent insulinotropic receptor, is a G protein-coupled receptor that is expressed in pancreatic beta-cells and intestinal L-cells. Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine (Cay-10172) and oleoyl ethanolamide (Cay-90265) increases intracellular cAMP levels and...
| Schlagworte: | JNJ-28630368, 4-[[1-[2-fluoro-4-(methylsulfonyl)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy]-1-piperidinecarboxylic acid,... |
| Anwendung: | GPR119 agonist |
| CAS | 832714-46-2 |
| MW: | 477.5 D |
ab 61,00 €
