Zu "821768-06-3" wurden 2 Artikel gefunden!
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JNJ-17203212
Artikelnummer: Cay30930-10
JNJ-17203212 is a transient receptor potential vanilloid 1 (TRPV1) antagonist (Ki = 72 nM for the recombinant guinea pig channel). It inhibits guinea pig TRPV1 channel activation induced by capsaicin (Cay-92350, Cay-10010743) or pH decrease (IC50s = 58 and 470 nM, respectively). JNJ-17203212 (20 mg/kg) reduces the...
| Schlagworte: | 4-[3-(trifluoromethyl)-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarboxamide |
| Anwendung: | TRPV1 antagonist |
| CAS | 821768-06-3 |
| MW: | 419.3 D |
ab 174,00 €
JNJ-17203212
Artikelnummer: TGM-T7526-100mg
Description: JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM). Target: TRP/TRPV Channel. Smiles: FC(F)(F)c1ccc(NC(=O)N2CCN(CC2)c2ncccc2C(F)(F)F)nc1. References: Wiskur B J , Tyler K , Campbelldittmeyer K , et al. A novel TRPV1 receptor antagonist...
| Anwendung: | TRPV1 antagonist |
| CAS | 821768-06-3 |
| MW: | 419.32 D |
ab 32,00 €
