Zu "82159-09-9" wurden 2 Artikel gefunden!
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Epalrestat
Artikelnummer: Cay15214-5
Epalrestat is an inhibitor of aldose reductase (IC50s = 0.01 and 0.26 µM for rat lens and human placenta aldose reductase, respectively). It inhibits glucose-induced sorbitol accumulation in isolated rat lens, rat sciatic nerve, and human erythrocytes (IC50s = 1.5, 5, and 1.5 µM, respectively). It decreases high...
| Schlagworte: | ONO-2235, 5Z-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid |
| Anwendung: | Aldose reductase inhibitor |
| CAS | 82159-09-9 |
| MW: | 319.4 D |
ab 110,00 €
Epalrestat
Artikelnummer: TGM-T1458-100mg
Description: Epalrestat (ONO2235), an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particularly in patients with limited microangiopathy and good glycemic control. Target:...
| Schlagworte: | ONO2235 |
| Anwendung: | Targets aldehyde reductase [EC:1.1.1.21] (AKR1B) |
| CAS | 82159-09-9 |
| MW: | 319.4 D |
ab 30,00 €
