Zu "82-08-6" wurden 4 Artikel gefunden!
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Rottlerin
Artikelnummer: TGM-T16791-10mg
Description: Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCdelta of 3-6 µM, PKCalpha,beta,gamma of 30-42 µM, PKCepsilon,eta,zeta of 80-100 µM). Rottlerin causes apoptosis via caspase 3 activation. Target: Autophagy, Apoptosis, CaMK, HIV...
| Schlagworte: | NSC 56346, Mallotoxin, NSC 94525 |
| Anwendung: | Broad specifity kinase inhibitor |
| CAS | 82-08-6 |
| MW: | 516.54 D |
ab 37,00 €
Rottlerin
Artikelnummer: Cay12006-10
Rottlerin was originally identified as an inhibitor of PKCdelta (IC50 = 3 µM), but can also inhibit CAM kinase III and a wide range of protein kinases, including PRAK and MAPKAP-K2 (IC50s = 1.9 and 5 µM, respectively). It can act as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling...
| Schlagworte: | Mallotoxin, NSC 56346, NSC 94525,... |
| Anwendung: | Broad specifity kinase inhibitor |
| CAS | 82-08-6 |
| MW: | 516.5 D |
ab 85,00 €
Rottlerin (Mallotoxin)
Artikelnummer: R3005-01.10
Rottlerin is an inhibitor of PRAK (IC50 1.9M), MAPKAP Kinase 2 (IC50 5.4M) and CaM Kinase III (3-6M). Rottlerin inhibits PMA-induced edema in mouse ear. For use as an Inhibitor of PRAK, MAPKAP kinase 2, and CaM Kinase III activity. Also shown to act as a direct mitochondrial uncoupler. Thought to stimulate autophagy...
| CAS | 82-08-6 |
ab 349,00 €
Rottlerin
Artikelnummer: AG-CN2-0526-M010
Anticancer agent that can inhibit cell growth, induce apoptosis, autophagy and cell cycle arrest, inhibit cell invasion and shows anti-angiogenic activity. OXPHOS inhibitor. Mitochondrial uncoupler that depolarizes the mitochondrial membrane potential, reduces cellular ATP levels, activates 5'-AMP-activated protein...
| Schlagworte: | Mallotoxin, NSC94525, NSC56346, Kamalin |
| Anwendung: | Anticancer agent, Apoptosis inducer |
| CAS | 82-08-6 |
| MW: | 516.5 D |
ab 50,00 €
