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Vesnarinone
Vesnarinone

Artikelnummer: Cay23489-1

Vesnarinone is an inhibitor of phosphodiesterase 3 (PDE3, IC50s = 10.7 and 13.2 µM for PDE3A and PDE3B, respectively). It also inhibits ether-a-go-go-related gene 1 (ERG1) channels (IC50 = 1.1 µM in HEK293T cells expressing human ERG1). Vesnarinone (3-300 µM) increases contractile tension in isolated ventricular...
Schlagworte: OPC 8212, 6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-2(1H)-quinolinone
Anwendung: PDE3 inhibitor
CAS 81840-15-5
MW: 395.5 D
ab 49,00 €
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Vesnarinone
Vesnarinone

Artikelnummer: TGM-T3465-100mg

Description: Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an...
Schlagworte: OPC-8212 , Arkin , Piteranometozine
Anwendung: Cardiotonic, Phosphodiesterase inhibitor
CAS 81840-15-5
MW: 395.45 D
ab 30,00 €
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