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JNJ-26483327
JNJ-26483327

Artikelnummer: Cay44468-1

JNJ-26483327 is an inhibitor of Met. It also inhibits EGFR, HER2, and HER4 (IC50s = 9.6, 18, and 40.3 nM, respectively). JNJ-26483327 (5 or 10 µM), in combination with trastuzumab, reduces HER2 phosphorylation in BT474 breast cancer cells. It decreases tumor volume when used in combination with trastuzumab in a...
Schlagworte: 17-bromo-1,8,9,10,11,12,13,14-octahydro-20-methoxy-13-methyl-4,6-ethenopyrimido[4,5-b][6,1,12]benzoxadiazacyclopentadecine
Anwendung: Met inhibitor
CAS 807640-87-5
MW: 457.37 D
ab 209,00 €
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BGB-102
BGB-102

Artikelnummer: TGM-T10531-10mg

Description: BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular degeneration and diseases associated with genetic disorders and malformations. Target: Src, EGFR, FLT, VEGFR. Smiles:...
Schlagworte: JNJ-26483327
CAS 807640-87-5
MW: 457.36 D
ab 310,00 €
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