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Simvastatin
Simvastatin

Artikelnummer: LKT-S3449.500

A potent HMG-CoA reductase inhibitor and hypocholesterolemic agent. Inhibits cell proliferation of human glioma cells and of acute myeloid leukemia cells. Anti-carcinogenic during the promotion phase of radiation-induced mammary tumors.
Anwendung: HMG-CoA reductase inhibitor
CAS 79902-63-9
MW: 418,57 D
ab 91,00 €
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Simvastatin
Simvastatin

Artikelnummer: TGM-T0687-10mg

Description: Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovascular disease. Target: Mitophagy, Autophagy, Apoptosis, Ferroptosis, HMG-CoA...
Schlagworte: MK-0733, MK 733
CAS 79902-63-9
MW: 418.57 D
ab 37,00 €
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Simvastatin
Simvastatin

Artikelnummer: Cay10010344-5

Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki = 0.12 nM). Simvastatin reduces plasma cholesterol levels in rats and dogs when administered at doses of 1.2 and 8 mg/kg, respectively. Simvastatin suppresses TNF-induced NF-kappaB activation (IC50 = ~13 µM) and potentiates apoptosis in human myeloid...
Schlagworte: MK-733,...
Anwendung: HMG-CoA reductase inhibitor
CAS 79902-63-9
MW: 418.6 D
ab 44,00 €
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Simvastatin
Simvastatin

Artikelnummer: AG-CN2-0052-M010

Synthetic analog of Lovastatin (Prod. No. AG-CN2-0051), potent competitive HMG-CoA reductase inhibitor, anti-hypercholesterolemic agent, cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids, inhibits the...
Schlagworte: MK-733, Synvinolin, BRN 4768038
Anwendung: NF-kappaB activation inhibitor
CAS 79902-63-9
MW: 495,7 D
ab 28,00 €
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