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TPI-1
Artikelnummer: TGM-T3962-100mg
Description: TPI-1 is a SHP-1 inhibitor. Target: Glucocorticoid Receptor, Phosphatase. Smiles: Clc1ccc(Cl)c(c1)C1=CC(=O)C=CC1=O. References: Kundu S, et al. Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents. J Immunol. 2010 Jun...
| Schlagworte: | TPI 1, TPI1 |
| Anwendung: | SHP1 inhibitor |
| CAS | 79756-69-7 |
| MW: | 253.08 D |
ab 48,00 €
TPI-1
Artikelnummer: Cay22480-1
TPI-1 is an inhibitor of protein tyrosine phosphatases. TPI-1 (10 ng/ml) increases phosphorylated substrates of the phosphatase SHP-1 in Jurkat T cells, including pLck-pY394, pZap70, and pSlp76. It is selective for SHP-1 over SHP-2, having low activity at the SHP-2 substrate pERK1/2. It increases pLck-pY394 levels...
| Schlagworte: | Tyrosine Phosphatase Inhibitor 1, 2-(2,5-dichlorophenyl)-2,5-cyclohexadiene-1,4-dione |
| Anwendung: | SHP1 inhibitor |
| CAS | 79756-69-7 |
| MW: | 253.1 D |
ab 52,00 €
