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Masitinib
Artikelnummer: TGM-T2609-100mg
Description: Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet. It has been available in Europe since the second part of 2009. In the USA it is...
| Schlagworte: | AB1010 |
| Anwendung: | Targets proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1] (KIT, SCFR, CD117) |
| CAS | 790299-79-5 |
| MW: | 498.64 D |
ab 31,00 €
Masitinib
Artikelnummer: Cay13105-10
Masitinib is an inhibitor of the receptor tyrosine kinase c-Kit (IC50 = 200 nM for the recombinant human enzyme). It is also an inhibitor of PDGFRalpha, PDGFRbeta, and Lyn B (IC50s = 540, 800, and 510 nM, respectively). Masitinib inhibits stem cell factor-induced proliferation of Ba/F3 cells expressing wild-type KIT...
| Schlagworte: | AB-1010, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]-benzamide |
| Anwendung: | c-Kit inhibitor |
| CAS | 790299-79-5 |
| MW: | 498.6 D |
ab 94,00 €
Masitinib
Artikelnummer: LKT-M0374.5
PDGFR and c-Kit inhibitor.
| Schlagworte: | AB1010, Masatinib, Masitinib (AB1010), Masivet,... |
| CAS | 790299-79-5 |
| MW: | 499 D |
ab 104,00 €
Masatinib
Artikelnummer: SYN-1053-M001
Soluble in DMSO or ethanol.Masitinib is a potent, orally available protein tyrosine kinase inhibitor targeting c-Kit, PDGFR and FGFR3. It demonstrates activity for Kit and PDGFR alpha/beta with IC(50) values of 200nM, 540nM and 800nM respectively. It shows weak inhibition of ABL and c-Fms. Target: c-Kit, PDGFR and...
| Schlagworte: | AB1010, Masivet |
| Anwendung: | c-Kit inhibitor |
| CAS | 790299-79-5 |
| MW: | 498,7 D |
ab 69,00 €
![Masitinib, Free Base (4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "Masitinib, Free Base (4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl")
