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Bisantrene
Artikelnummer: Cay40986-10
Bisantrene is an inhibitor of fat mass and obesity-associated protein (FTO, IC50 = 142.6 nM in a cell-free assay). It decreases the viability of Mono-Mac-6, NOMO-1, U937, MV4-11, and ML-2 acute myeloid leukemia (AML) cells (IC50s = 58.9-175.9 nM), as well as increases the levels of N6-methyladenosine (m6A) in...
| Schlagworte: | Bisantrenum, 9,10-bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone] 9,10-anthracenedicarboxaldehyde |
| Anwendung: | FTO inhibitor, antineoplastic |
| CAS | 78186-34-2 |
| MW: | 398.5 D |
ab 54,00 €
Bisantrene
Artikelnummer: TGM-T4047-100mg
Description: Bisantrene (CL216942) is an anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but...
| Schlagworte: | CL216942 |
| Anwendung: | FTO inhibitor, antineoplastic |
| CAS | 78186-34-2 |
| MW: | 398.46 D |
ab 34,00 €
