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Triparanol
Artikelnummer: Cay20918-1
Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 µM), which is an enzyme involved in the biosynthesis of cholesterol. It has antitumor properties, such as decreasing proliferation and inducing apoptosis in many cancer cell lines and slowing tumor growth in a mouse xenograft model. It...
| Schlagworte: | MER-29, NSC 65345, 4-chloro-alpha-[4-[2-(diethylamino)ethoxy]phenyl]-alpha-(4-methylphenyl)-benzeneethanol |
| Anwendung: | Delta(24)-sterol reductase inhibitor |
| CAS | 78-41-1 |
| MW: | 438 D |
ab 81,00 €
Triparanol
Artikelnummer: TGM-T26296-10mg
Description: Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic...
| Schlagworte: | MER-29, NSC 65345, NSC65345, NSC-65345 |
| CAS | 78-41-1 |
| MW: | 438 D |
ab 281,00 €
