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Butyrolactone 3
Artikelnummer: Cay12095-1
Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. Butyrolactone 3 specifically inhibits the histone acetyltransferase Gcn5 with an IC50 value of 100 µM and has an affinity to the Gcn5...
| Schlagworte: | rel-tetrahydro-4-methylene-5-oxo-2R-propyl-3S-furancarboxylic acid |
| Anwendung: | HAT inhibitor |
| CAS | 778649-18-6 |
| MW: | 184.2 D |
ab 73,00 €
Butyrolactone 3
Artikelnummer: AG-CR1-3522-M002
Specific histone acetyltransferase Gcn5 inhibitor. Anticancer compound. Pre-mRNA splicing inhibitor. Blocks splicing before the first catalytic steps. Potential anti-inflammatory compound.
| Schlagworte: | (2R,3S)-rel-Tetrahydro-4-methylene-5-oxo-2-propyl-3-furancarboxylic acid, MB-3 |
| Anwendung: | Histone acetyltransferase Gcn5 inhibitor |
| CAS | 778649-18-6 |
| MW: | 184 D |
105,00 €
