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Metoprine
Artikelnummer: TGM-T8548-100mg
Description: Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity. Target: Histone Methyltransferase, Histamine Receptor, Antifolate. Smiles: CC=1C(=C(N)N=C(N)N1)C2=CC(Cl)=C(Cl)C=C2. References: Junichi Kitanaka, et al. Brain Histamine N-Methyltransferase...
| Anwendung: | Antineoplastic |
| CAS | 7761-45-7 |
| MW: | 269.13 D |
ab 52,00 €
Metoprine
Artikelnummer: Cay43098-10
Metoprine is an inhibitor of histamine N-methyltransferase (HNMT, IC50 = 91 nM). It is also an inhibitor of dihydrofolate reductase (Dhfr, IC50s = 1, 1. and 60 µM for the chicken, rat, and T. equiperdum enzymes, respectively). Metoprine (10 mg/kg) increases the levels of histamine in mouse cerebral cortex,...
| Schlagworte: | DDMP, NSC 19494, NSC 7364, 5-(3,4-dichlorophenyl)-6-methyl-2,4-pyrimidinediamine |
| Anwendung: | HNMT inhibitor, antineoplastic |
| CAS | 7761-45-7 |
| MW: | 269.13 D |
ab 153,00 €
