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PTP1B Inhibitor
Artikelnummer: Cay15782-1
Protein tyrosine phosphatase 1B (PTP1B) has critical roles in cell signaling relevant to diabetes, obesity, and cancer. PTP1B inhibitor is a cell-permeable allosteric inhibitor of PTP1B (IC50s = 4 and 8 µM for 403 and 298 residue PTP1B forms, respectively). It binds reversibly and non-competitively, altering the...
| Schlagworte: | Protein Tyrosine Phosphatase 1B Inhibitor,... |
| Anwendung: | Cell-permeable allosteric PTP1B inhibitor |
| CAS | 765317-72-4 |
| MW: | 741.5 D |
ab 95,00 €
NEU
PTP1B-IN-4
Artikelnummer: TGM-T24073-10mg
Description: PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 µM. PTP1B-IN-4 can be used in studies about obesity and diabetes. Target: Phosphatase. Smiles: C(=O)(C=1C=2C(OC1CC)=CC(S(NC3=CC=C(S(NC4=NC=CS4)(=O)=O)C=C3)(=O)=O)=CC2)C5=CC(Br)=C(O)C(Br)=C5. References: Steinhauer J, et al....
| Schlagworte: | FRJ, PTP1B-IN-2, PTP1B IN 2, PTP1B-inhibitor-4, PTP1B-inhibitor-2, NUN 17724, NUN17724, PTP1BIN2, PTP1B inhibitor 2, PTP1B... |
| CAS | 765317-72-4 |
| MW: | 741.45 D |
ab 206,00 €
