Zu "763113-22-0" wurden 4 Artikel gefunden!
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Olaparib
Artikelnummer: Cay10621-5
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM,...
| Schlagworte: | AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
| Anwendung: | PARP1 / PARP2 inhibitor |
| CAS | 763113-22-0 |
| MW: | 434.5 D |
ab 66,00 €
Olaparib
Artikelnummer: LKT-O4402.5
A potent orally active inhibitor of PARP (Poly(adenosine diphosphate-ribose) polymerase)-1 and PARP-2.
| Schlagworte: | AZD2281, KU-0059436 |
| Anwendung: | Poly(adenosine diphosphate-ribose) polymerase inhibitor |
| CAS | 763113-22-0 |
| MW: | 434,47 D |
ab 108,00 €
Olaparib (AZD-2281, KU-0059436, KU 59436, Lynparza,...
Artikelnummer: LC-O-9201_1g
Soluble in DMSO at 33 mg/mL, soluble in ethanol at 1.7 mg/mL with slight warming, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Schlagworte: | AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
| Anwendung: | PARP1 / PARP2 inhibitor |
| CAS | 763113-22-0 |
| MW: | 434,46 D |
ab 124,00 €
Olaparib
Artikelnummer: CDX-O0144-G001
Off-white to beige powder. Soluble in DMSO (20mg/ml) or DMF (10mg/ml). Slightly soluble in ethanol (1mg/ml). Chemical. CAS: 763113-22-0. Formula: C24H23FN4O3. MW: 434.47. Synthetic. Olaparib is a cell-permable potent inhibitor of PARP1 and PARP2 (IC50=5 and 1nM, respectively) but is less effective against the PARP...
| Schlagworte: | AZD 2281, Ku-0059436, Lynparza,... |
| CAS | 763113-22-0 |
| MW: | 434,47 D |
ab 122,00 €
