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TAE684
TAE684

Artikelnummer: Cay17670-5

Human anaplastic lymphoma kinase (ALK) is an oncogene that is amplified in neuroblastomas and when juxtaposed with various fusion partners, its constitutive kinase activity is associated with the development of a type of anaplastic large cell lymphoma (ALCL). TAE684 is an ALK inhibitor that blocks the proliferation...
Schlagworte: NVP-TAE684,...
Anwendung: ALK inhibitor
CAS 761439-42-3
MW: 614.2 D
ab 52,00 €
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TAE-684
TAE-684

Artikelnummer: SYN-1159-M001

Soluble in DMSO or ethanol. TAE684 is a potent and selective ALK inhibitor with an IC(50) of 3nM. It is 100-fold more sensitive for ALK over InsR. Target: ALK , Kinase Group: RTK , Substrate: Tyrosine
Schlagworte: NVP-TAE684
Anwendung: ALK inhibitor
CAS 761439-42-3
MW: 614,2 D
ab 139,00 €
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NVP-TAE684
NVP-TAE684

Artikelnummer: LKT-N8760.1

ALK, c-Fes, LRRK2 inhibitor.
Schlagworte: TAE684
Anwendung: ALK, c-Fes, LRRK2 inhibitor
CAS 761439-42-3
MW: 614.21 D
ab 142,00 €
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NVP-TAE 684
NVP-TAE 684

Artikelnummer: TGM-T2251-5mg

Description: NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM). Target: Apoptosis, ALK. Smiles: N(C1=C(S(C(C)C)(=O)=O)C=CC=C1)C2=NC(NC3=C(OC)C=C(C=C3)N4CCC(CC4)N5CCN(C)CC5)=NC=C2Cl. References: Galkin AV, et al. Proc Natl Acad Sci U S A, 2007, 104(1), 270-275.
Schlagworte: TAE684
Anwendung: ALK inhibitor
CAS 761439-42-3
MW: 614.2 D
ab 52,00 €
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