Zu "75747-14-7" wurden 5 Artikel gefunden!
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Tanespimycin
Artikelnummer: TGM-T6290-5mg
Description: Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM). Target: Antibacterial, Apoptosis, HSP, Autophagy, Antibiotic, Mitophagy. Smiles:...
| Schlagworte: | KOS 953, NSC 330507, 17-AAG, CP 127374 |
| Anwendung: | Antineoplastic, Hsp 90 inhibitor |
| CAS | 75747-14-7 |
| MW: | 585.69 D |
ab 40,00 €
17-AAG
Artikelnummer: Cay11039-1
17-AAG is an inhibitor of heat shock protein 90 (Hsp90) and a derivative of geldanamycin (Cay-13355) that selectively inhibits BT474 tumor cell Hsp90 over fibroblast Hsp90 (IC50s = 5 and 943 nM, respectively). It inhibits the growth of prostate cancer cell lines (IC50s = 25-45 nM) and promotes the degradation of...
| Schlagworte: | BMS 722782, CP 127374, KOS 953, NSC 330507, Tanespimycin, 17-demethoxy-17-(2-propenylamino)-geldanamycin |
| Anwendung: | Hsp90 inhibitor |
| CAS | 75747-14-7 |
| MW: | 585.7 D |
ab 52,00 €
17-AAG
Artikelnummer: BVT-0244-M005
Potent, less toxic analog of geldanamycin, Inhibits the essential ATPase activity of HSP90, Telomerase activity inhibitor, Apoptosis inducer, Antitumor compound. Semi-synthetic derivative from geldanamycin.
| Schlagworte: | 17-(Allylamino)-17-desmethoxygeldanamycin |
| Anwendung: | Hsp90 inhibitor |
| CAS | 75747-14-7 |
| MW: | 585,7 D |
ab 25,00 €
17-AAG
Artikelnummer: LKT-A0025.5
An anologue of geldanamycin. It is a Hsp90 antagonist that induces apoptosis in human leukemiacells. It has been shown to enhance paclitaxel-mediated cytotoxicity and downregulate vascular endothelial factor expression.
| Anwendung: | Hsp90 antagonist |
| CAS | 75747-14-7 |
| MW: | 585,69 D |
ab 92,00 €
17-AAG (17-allylamino-17-demethoxygeldanamycin,...
Artikelnummer: A0001-85.250
Semi-synthetic derivative of geldanamycin, demonstrating greater stability and lower in vivo toxicity than its parent compound. 17-AAG binds specifically to heat shock protein Hsp90 in a manner similar to geldanamycin, but the binding is weaker. Solubility: Soluble in DMSO at 150mg/ml, soluble in ethanol at 5mg/ml,...
| CAS | 75747-14-7 |
| MW: | 585.69 |
454,00 €
