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Leflunomide
Leflunomide

Artikelnummer: Cay14860-25

Leflunomide is a synthetic isoxazol and a prodrug form of A-771726 (Cay-14404), a dihydroorotate dehydrogenase inhibitor. Leflunomide inhibits de novo pyrimidine synthesis to regulate T lymphocyte progression through the cell cycle. It inhibits proliferation and activation of T cells when used at concentrations of...
Schlagworte: Arava, HW 486, SU 101, 5-methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide
Anwendung: Immunosuppressant, pyrimidine synthesis inhibitor, dihydroorotate dehydrogenase inhibitor
CAS 75706-12-6
MW: 270.2 D
ab 49,00 €
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Leflunomide
Leflunomide

Artikelnummer: LKT-L1817.1

Leflunomide is a pyrimidine biosynthesis inhibitor. It is an established disease-modifying antirheumatic drug. It has been approved for treatment of rheumatoid arthritis (RA) and may also be useful in treating patients with Felty´s syndrome. It is suggested that supression of TNF signalling is one of the...
Schlagworte: HWA-486
Anwendung: Pyrimidine biosynthesis inhibitor
CAS 75706-12-6
MW: 270,21 D
ab 141,00 €
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Leflunomide
Leflunomide

Artikelnummer: TGM-T1159-100mg

Description: Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. Target: Others, AhR, Dehydrogenase. Smiles: CC1=C(C=NO1)C(=O)NC1=CC=C(C=C1)C(F)(F)F. References: Davis JP, et al. Biochemistry, 1996, 35(4), 1270-1273.
Schlagworte: SU101, HWA486, RS-34821
CAS 75706-12-6
MW: 270.21 D
ab 38,00 €
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