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Ingenol mebutate
Ingenol mebutate

Artikelnummer: TGM-TN1047-10mg

Description: Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-alpha, PKC-beta, PKC-gamma, PKC-delta, and PKC-epsilon with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity. Target: PKC, HIV Protease, gp120/CD4....
Schlagworte: Ingenol 3-Angelate, PEP005
CAS 75567-37-2
MW: 430.53 D
ab 63,00 €
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Ingenol-3-angelate
Ingenol-3-angelate

Artikelnummer: AG-CN2-0012-M001

Specific protein kinase C (PKC) activator, Selective activator of PKC isoforms, like PKCtheta in T cells, Antiproliferative and proapoptotic (necrotic), Immunostimulant, Chemotherapeutic, Anticancer compound, Efficacious agent against actinic kerastosis, Antileukemic. Isolated from Euphorbia peplus L.
Schlagworte: PEP005, I3A
Anwendung: Protein kinase C (PKC) activator
CAS 75567-37-2
MW: 430,5 D
ab 132,00 €
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Ingenol-3-angelate
Ingenol-3-angelate

Artikelnummer: Cay16207-10

Ingenol-3-angelate is a hydrophobic diterpene ester that can be isolated from the euphorb E. peplus. It rapidly induces cell death in proliferating keratinocytes through plasma membrane and mitochondrial disruption, although it can also initiate apoptosis in some cancer cell lines (LD90 = ~190 µM). Secondarily,...
Schlagworte: 3-Ingenyl Angelate, Ingenol Mebutate, PEP005, Picato(R), 2Z-methyl-2-butenoic acid,...
Anwendung: Keratinocyte cell death inducer
CAS 75567-37-2
MW: 430.5 D
ab 57,00 €
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