Zu "752253-39-7" wurden 2 Artikel gefunden!
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Crinecerfont
Artikelnummer: Cay45039-1
A CRF1 antagonist (Ki = 1.9 nM), selective for CRF1 over CRF2alpha and a panel of 125 receptors, transporters, ion channels, and enzymes at 10 µM, inhibits CRF-induced cAMP production in Y79 cells (IC50 = 3 nM) and CRF-induced ACTH secretion in AtT-20 cells at 3, 30, and 100 nM, prevents restraint stress-induced...
| Schlagworte: | NBI 74788, SSR 125543,... |
| Anwendung: | Corticotropin-releasing factor receptor 1 (CRHR1/CRF1) antagonist |
| CAS | 752253-39-7 |
| MW: | 483.04 D |
ab 92,00 €
Crinecerfont
Artikelnummer: TGM-T31095-10mg
Description: Crinecerfont (SSR-125543) is a selective antagonist of corticotropin-releasing factor 1 receptor (CRF1) and can be used in studies about Classic congenital adrenal hyperplasia. Target: CRFR. Smiles: [C@H](N(CC#C)C1=NC(=C(C)S1)C2=C(Cl)C=C(OC)C(C)=C2)(CC3CC3)C4=CC(F)=C(C)C=C4. References: Philbert J, et...
| Schlagworte: | SSR125543, SSR-125543A, SSR 125543A, SSR125543A, SSR-125543, SSR 125543 |
| Anwendung: | Targets corticotropin releasing hormone receptor 1 (CRHR1) |
| CAS | 752253-39-7 |
| MW: | 483.04 D |
ab 87,00 €
