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CyPPA
CyPPA

Artikelnummer: TGM-T20968-100mg

Description: CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolarization. Target: Dopamine Receptor, Potassium Channel. Smiles: Cc1cc(C)n(n1)-c1nc(C)cc(NC2CCCCC2)n1. References: Herrik KF, Redrobe JP, Holst D,...
CAS 73029-73-9
MW: 285.39 D
ab 38,00 €
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CyPPA
CyPPA

Artikelnummer: Cay15614-10

CyPPA is a positive modulator of the small-conductance calcium-activated potassium channels KCa2.2/SK2 and KCa2.3/SK3 (EC50s = 14 and 5.6 µM, respectively). It is inactive on both KCa2.1/SK1 and the intermediate conductance calcium-activated potassium channel, KCa3.1/SK4. At KCa2.3/SK3, CyPPA increases the apparent...
Schlagworte: N-cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl-4-pyrimidinamine
Anwendung: Small conductance calcium-activated channel SK2/SK3 modulator
CAS 73029-73-9
MW: 285.4 D
ab 174,00 €
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