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Acifran
Acifran

Artikelnummer: Cay34556-1

Acifran is a niacin receptor agonist. It binds to hydroxycarboxylic acid receptor 2 (HCA2), known previously as G protein-coupled receptor 109A (GPR109A) and niacin receptor 1, with an IC50 value of 1.12 µM, as well as induces ERK1/2 phosphorylation in CHO-K1 cells expressing HCA2 or HCA3, also known as GPR109B and...
Schlagworte: (±)-Acifran, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
Anwendung: Niacin receptor agonist, antidyslipidemic, hyperlipoproteinemic
CAS 72420-38-3
MW: 218.2 D
ab 44,00 €
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Acifran
Acifran

Artikelnummer: TGM-T22547-100mg

Description: Acifran (AY 25712) is an HM74A/GPR109A and GPR109B agonist and displays antihyperlipidemic activity. Target: GPR. Smiles: CC1(OC(=CC1=O)C(O)=O)c1ccccc1. References: M N Cayen, et al. The metabolic disposition of acifran, a new antihyperlipidemic agent, in rats and dogs. Xenobiotica. 1986 Mar,16(3):251-63.
Schlagworte: AY 25712
Anwendung: Antidyslipidemia (hyperlipoproteinemic)
CAS 72420-38-3
MW: 218.21 D
ab 39,00 €
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