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PF-562271
Artikelnummer: SYN-1064-M001
Soluble in DMSO or ethanol. PF-562,271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 catalytic activity with a IC(50) of 1.5 and 14nM, respectively. In addition, PF-562,271 displayed robust inhibition in an inducible cell-based assay measuring phospho-FAK with an IC(50) of 5nM. PF-562,271 was...
| Schlagworte: | PF562271, PF-562,271 |
| Anwendung: | FAK / Pyk2 inhibitor |
| CAS | 717907-75-0 |
| MW: | 507,5 D |
ab 123,00 €
PF-562271
Artikelnummer: TGM-T2465-100mg
Description: PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM). Target: CDK, FAK, PYK2. Smiles: CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O. References: Roberts WG, et al. Cancer Res, 2008, 68(6), 1935-1944.
| Schlagworte: | PF562271, PF 562271 |
| Anwendung: | FAK / Pyk2 inhibitor |
| CAS | 717907-75-0 |
| MW: | 507.49 D |
ab 55,00 €
