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ML-141
Artikelnummer: Cay18496-1
Cdc42 is a member of the Rho GTPase subfamily that has roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. It cycles between a GTP-bound active state and a GDP-bound inactive state. ML-141 is a noncompetitive, allosteric inhibitor of Cdc42 (EC50 = 2.1 µM) with no...
| Schlagworte: | CID2950007, 4-[4,5-dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]-benzenesulfonamide |
| Anwendung: | Allosteric Cdc42 inhibitor |
| CAS | 71203-35-5 |
| MW: | 407.5 D |
ab 49,00 €
ML141
Artikelnummer: TGM-T2463-100mg
Description: ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM). Target: CDK, Apoptosis, Ras. Smiles: COC1=CC=C(C=C1)C1CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C1=CC=CC=C1. References: Surviladze Z, et al. National Center for Biotechnology...
| Schlagworte: | CID-2950007 |
| Anwendung: | Allosteric Cdc42 inhibitor |
| CAS | 71203-35-5 |
| MW: | 407.49 D |
ab 32,00 €
