Zu "698387-09-6" wurden 4 Artikel gefunden!
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Neratinib
Artikelnummer: Cay18404-10
Neratinib is a dual inhibitor of EGFR and HER2 (IC50s = 92 and 59 nM, respectively). It is selective for EGFR and HER2 over a panel of 12 kinases (IC50s = >5,000 nM) but does inhibit VEGFR2 and Src (IC50s = 800 and 1,400 nM, respectively). Neratinib inhibits the proliferation of NCI H508 colorectal cancer cells...
| Schlagworte: | HKI-272,... |
| Anwendung: | EGFR/ ERBB2 inhibitor |
| CAS | 698387-09-6 |
| MW: | 557 D |
ab 58,00 €
Neratinib, Free Base
Artikelnummer: LC-N-6404_100mg
Solubility: Soluble in DMSO at 2 mg/mL with warming, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 5-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility. Neratinib, also known as HKI-272, is considered to...
| Schlagworte: | HKI-272 |
| Anwendung: | EGFR/ ERBB2 inhibitor |
| CAS | 698387-09-6 |
| MW: | 557,04 D |
ab 175,00 €
Neratinib
Artikelnummer: CDX-N0326-M050
Neratinib is a cell-permable, irreversible, selective inhibitor of the HER2 kinase (IC50=59nM) and EGFR (IC50=92nM) by preventing phosphorylation of these proteins by their respective kinases. It also potently inhibits several mutants of HER2 and shows 10-fold or greater selectivity over a wide variety of other...
| Schlagworte: | HKI-272 |
| Anwendung: | Antineoplastic, Cell-permable, irreversible, selective HER2 / EGFR inhibitor |
| CAS | 698387-09-6 |
| MW: | 557 D |
ab 122,00 €
Neratinib
Artikelnummer: LKT-N1868.5
It is an orally active, irreversible tyrosine kinase inhibitor of the HER-2 and EGFR.
| Schlagworte: | HKI-272,... |
| CAS | 698387-09-6 |
| MW: | 557.04 D |
ab 129,00 €
