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ZM 306416
Artikelnummer: Cay16968-5
ZM 306416 is an inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase that antagonizes the activity of KDR and Flt VEGF receptors with IC50 values of 100 nM and 2 µM, respectively. It has also been reported to inhibit EGFR kinase with an IC50 value of 98%. Formulation: (Request formulation...
| Schlagworte: | CB-676475, N-(4-chloro-2-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine |
| Anwendung: | VEGFR inhibitor |
| CAS | 690206-97-4 |
| MW: | 333.7 D |
ab 69,00 €
ZM 306416
Artikelnummer: TGM-T1754-100mg
Description: ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 µM), can also inhibit EGFR (IC50<10 nM). Target: Bcr-Abl, Src, VEGFR. Smiles: COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC. References: Antczak C, et al. J Biomol Screen, 2012, 17(7), 885-899.
| Schlagworte: | CB 676475 |
| Anwendung: | VEGFR inhibitor |
| CAS | 690206-97-4 |
| MW: | 333.74 D |
ab 39,00 €
