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Tivozanib (hydrate)
Artikelnummer: Cay18493-1
Tivozanib is an orally available, selective VEGFR inhibitor with IC50 values of 0.21, 0.16, and 0.24 nM for VEGFR1, VEGFR2, and VEGFR3, respectively. It can also inhibit c-Kit and PDGFRbeta with IC50 values of 1.63 and 1.72 nM, respectively. When administered to athymic rats, tivozanib was shown to decrease the...
| Schlagworte: | AV-951, KRN 951, N-[2-chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)-urea, monohydrate |
| Anwendung: | VEGFR inhibitor |
| CAS | 682745-40-0 |
| MW: | 472.9 D |
ab 73,00 €
