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CBR-5884
Artikelnummer: Cay19236-5
CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 µM. It does not affect other NAD+-dependent dehydrogenases, including lactate dehydrogenase and malate dehydrogenase 1. CBR-5884 inhibits the proliferation of...
| Schlagworte: | 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylic acid, ethyl ester |
| Anwendung: | PHGDH inhibitor |
| CAS | 681159-27-3 |
| MW: | 336.4 D |
ab 38,00 €
CBR-5884
Artikelnummer: TGM-T14884-100mg
Description: CBR-5884 is an selective, active of phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 33 µM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of...
| Anwendung: | PHGDH inhibitor |
| CAS | 681159-27-3 |
| MW: | 336.39 D |
ab 38,00 €
