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TG 100-115
Artikelnummer: Cay10010512-1
TG 100-115 is an inhibitor of PI3Kgamma and PI3Kdelta (IC50s = 0. and 0. µM, respectively). It is selective for PI3Kgamma and PI3Kdelta over PI3Kalpha and PI3Kbeta (IC50s = 1. and 1. µM) and a panel of 140 additional kinases but does inhibit eight kinases in the panel. TG 100-115 also inhibits the kinase activity of...
| Schlagworte: | 3,3'-(2,4-diamino-6,7-pteridinediyl)bis-phenol |
| Anwendung: | PI3Kgamma/PI3Kdelta inhibitor |
| CAS | 677297-51-7 |
| MW: | 346.3 D |
ab 38,00 €
TG100-115
Artikelnummer: LKT-T2402.5
TG100-115 is an inhibitor of p110 PI3K and p110 PI3K that exhibits anti-inflammatory and anti-asthma activities. TG100-115 decreases pulmonary eosinophil levels and accumulation of IL-13 and mucin in animal models of asthma and chronic obstructive pulmonary disorder (COPD), decreasing inflammation. TH100-115 also...
| Anwendung: | PI3K gamma / delta inhibitor |
| CAS | 677297-51-7 |
| MW: | 346.34 D |
ab 202,00 €
TG100115
Artikelnummer: SYN-1105-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. TG100115 inhibits PI3K gamma and delta, with IC(50) values of 83 and 235nM, respectively. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
| Schlagworte: | TG-100115 |
| Anwendung: | PI3K gamma / delta inhibitor |
| CAS | 677297-51-7 |
| MW: | 346,3 D |
ab 154,00 €
TG100-115
Artikelnummer: TGM-T2672-100mg
Description: TG100-115 is a PI3Kgamma/delta inhibitor (IC50: 83/235 nM), with fewer effects on PI3Kalpha/beta. Target: PI3K. Smiles: Nc1nc(N)c2nc(-c3cccc(O)c3)c(nc2n1)-c1cccc(O)c1. References: Doukas J, et al. Proc Natl Acad Sci U S A, 2006, 103(52), 19866-119871.
| CAS | 677297-51-7 |
| MW: | 346.34 D |
ab 35,00 €
