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Thapsigargin
Artikelnummer: Cay10522-1
Thapsigargin is an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50 = ~30 nM for the rat liver microsomal enzyme), an ER stress inducer, and a sesquiterpene lactone that has been found in Thapsia. It increases intracellular calcium levels in isolated rat hepatocytes (EC50 = ~80 nM) and...
| Schlagworte: | (3S,3aS,4R,6R,7S,8R)-6-acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-(((Z)-2-methylbut-2-enoyl)oxy)-2-oxo-2,3,3a... |
| Anwendung: | SERCA inhibitor |
| CAS | 67526-95-8 |
| MW: | 650.8 D |
ab 75,00 €
Thapsigargin (high purity)
Artikelnummer: AG-CN2-0003-M001
Colorless to white amorphous powder. Soluble in DMSO or 100% ethanol. Chemical. CAS: 67526-95-8. Formula: C34H50O12. MW: 650.8. Isolated from Thapsia garganica. Intracellular Ca2+ signaling probe. Specific and sensitive inhibitor of SERCA. Non-TPA/PMA tumor promoter. Histamine release inducer. Apoptosis inducer....
| Anwendung: | SERCA inhibitor, Ca2+ releaser |
| CAS | 67526-95-8 |
| MW: | 650,8 D |
ab 77,00 €
Thapsigargin
Artikelnummer: TGM-TQ0302-1mg
Description: Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking the ability of cells to pump calcium into the sarcoplasmic and endoplasmic...
| Anwendung: | SERCA inhibitor, Ca2+ releaser |
| CAS | 67526-95-8 |
| MW: | 650.75 D |
ab 81,00 €
Thapsigargin
Artikelnummer: LKT-T2801.5
Thapsigargin is isolated from Thapsia garganica. It is a cell permeable intracellular calcium releaser and tumor promoter.
| Schlagworte: | Thapsigargine, Tg |
| Anwendung: | SERCA inhibitor, Ca releaser |
| CAS | 67526-95-8 |
| MW: | 650,75 D |
ab 178,00 €
Thapsigargin
Artikelnummer: T3705.1
Potent, cell permeable IP3-independent intracellular calcium releaser. Solubility: Soluble in DMSO or ethanol. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
| CAS | 67526-95-8 |
| MW: | 650.75 |
169,00 €
Thapsigargin
Artikelnummer: CDX-T0284-M001
Thapsigargin is a non-competitive, cell permeable inhibitor of calcium transport by SERCAs (IC50 values are cell type-dependent and range from ~2-80 nM). Inhibition of SERCAs leads to an increase in intracellular calcium, which has been linked to cell activation, release of histamine from mast cells, and increased...
| Anwendung: | SERCA calcium transport inhibitor |
| CAS | 67526-95-8 |
| MW: | 650.75 D |
ab 108,00 €