Zu "670220-88-9" wurden 3 Artikel gefunden!
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Crenolanib
Artikelnummer: Cay18873-5
Crenolanib is an orally bioavailable, selective inhibitor of type III tyrosine kinases with nanomolar potencies against platelet-derived growth factor receptor alpha (PDGFRalpha) and PDGFRbeta and Fms-related tyrosine kinase 3 (FLT3, IC50s = 11, 3.2, and 4 nM, respectively). It also inhibits medically-relevant...
| Schlagworte: | CP 868,596, 1-[2-[5-[(3-methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine |
| Anwendung: | PDGFR tyrosine kinase inhibitor |
| CAS | 670220-88-9 |
| MW: | 443.5 D |
ab 71,00 €
Crenolanib
Artikelnummer: LKT-C6818.1
FLT3, PDGFR inhibitor.
| Schlagworte: | CP-868596 |
| Anwendung: | PDGFR tyrosine kinase inhibitor |
| CAS | 670220-88-9 |
| MW: | 443.54 D |
ab 166,00 €
Crenolanib
Artikelnummer: TGM-T2677-100mg
Description: Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRalpha/beta and FLT3 (IC50s: 11, 3.2, and 4 nM). Target: Autophagy, FLT, PDGFR. Smiles: CC1(COc2ccc3n(cnc3c2)-c2ccc3cccc(N4CCC(N)CC4)c3n2)COC1. References: Heinrich MC, et al.Crenolanib inhibits the...
| Schlagworte: | CP-868596, ARO 002 |
| Anwendung: | Targets fms-related tyrosine kinase 3 [EC:2.7.10.1] (FLT3, FLK2, CD135) |
| CAS | 670220-88-9 |
| MW: | 443.54 D |
ab 50,00 €
