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PG-931
Artikelnummer: TGM-TP1953-1mg
Description: Potent and selective melanocortin 4 (MC4) receptor agonist (IC50 values are 0.58 and 55 nM for human MC4 and MC3 receptors respectively). Produces a rapid and dose dependent restoration of cardiovascular and respiratory function in hemorrhage-shocked rats. References: Giuliani et al (2007) Selective...
| Schlagworte: | PG 931 |
| CAS | 667430-81-1 |
| MW: | 1180.41 D |
119,00 €
PG-931
Artikelnummer: Cay41551-1
A peptide MC4R agonist, increases intracellular cAMP levels in CHO cells expressing MC4R (EC50 = 0.42 nM), selectively binds to MC4R over MC3R and MC5R (IC50s = 0.58, 55, and 2.4 nM, respectively), increases MAP, pulse pressure, and respiratory rate in a rat model of hemorrhagic shock in a dose-dependent manner and...
| Schlagworte: | Ac-Nle-cyclic[Asp-Pro-D-Phe-Arg-Trp-Lys]-Pro-Val-NH2, (2?7)-lactam... |
| Anwendung: | Peptide MC4R agonist |
| CAS | 667430-81-1 |
| MW: | 1180.4 D |
ab 53,00 €
