Zu "656247-17-5" wurden 3 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
BIBF 1120
Artikelnummer: Cay11022-10
BIBF 1120 is an inhibitor of the receptor tyrosine kinases VEGFR, FGFR, and PDGFR (IC50s = 13-34, 37-610, 59, and 65 nM for VEGFR1-3, FGFR1-4, PDGFRalpha, and PDGFRbeta, respectively). It is selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases but does inhibit FLT3, LCK, LYN, and Src (IC50s = 16-156 nM)....
| Schlagworte: | Nintedanib,... |
| Anwendung: | Receptor tyrosine kinase inhibitor |
| CAS | 656247-17-5 |
| MW: | 539.6 D |
ab 60,00 €
Nintedanib, Free Base
Artikelnummer: LC-N-9077_25mg
Solubility: Soluble in DMSO at 25 mg/mL with warming, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility. This product was previously Cat. No. I-9077,...
| Schlagworte: | BIBF1120, Intedanib, Vargatef |
| Anwendung: | Antifibrosis, Tyrosine kinase inhibitor |
| CAS | 656247-17-5 |
| MW: | 539.62 D |
ab 82,00 €
Nintedanib (free base)
Artikelnummer: CDX-N0321-M025
Nintedanib is an orally bioavailable and potent triple angiokinase inhibitor with potential antiangiogenic and antineoplastic activities. It targets the proangiogenic pathways mediated by the the receptor tyrosine kinases VEGFR1/2/3 (IC50=13-34nM), FGFR1/2/3 (IC50=37-108nM) and PDGFRalpha/beta (IC50=59-65nM), which...
| Schlagworte: | BIBF-1120, BIBF1120 |
| Anwendung: | Antiangiogenic / antineoplastic tyrosine kinase inhibitor |
| CAS | 656247-17-5 |
| MW: | 539.6 D |
ab 68,00 €
